Protein Misfolding and Pathological Aggregation
9 papers0 projects
Yiming Tang唐一鸣
Postdoctoral Researcher · Fudan University
Computational physicist working on the intersection of physics and biology.
I am a postdoctoral researcher in the Department of Physics at Fudan University in Shanghai. Under the supervision of Professor Guanghong Wei, I combine multiscale biomolecular simulations and machine learning to investigate the physical mechanisms underlying living systems and biological processes. For academic collaboration, please contact me at [email protected].
Research at a glanceUpdated 2026-09-17
58Publications
1,759Total citations
23H-index
5Research themes
Research interests
Molecular Intervention and Drug Design for Disease-Associated Proteins
11 papers1 project
Biomolecular Phase Separation and Condensate Phase Transitions
12 papers2 projects
Biomolecular Self-Assembly and Functional Materials
20 papers0 projects
Protein Conformational Dynamics and Allosteric Regulation
7 papers0 projects
Selected publications
View all publicationsAlzheimer’s Aβ catalyzes Tau phase separation and aggregation via early nanocluster solubilization
Stoichiometry-Controlled Structural Transformation of Diphenylalanine Nanoassemblies through Coassembly with Charged Dipeptides
Dissecting the Molecular Determinants of α‐synuclein Phase Separation and Condensate Aging: The Pivotal Role of β‐Sheet‐Rich Motifs
Prediction and characterization of liquid-liquid phase separation of minimalistic peptides
About
I earned a bachelor's degree in physics and a PhD in condensed matter physics from Fudan University, where Professor Guanghong Wei supervised my doctoral research. My collaborators include Ehud Gazit at Tel Aviv University, Jinghui Luo at the Paul Scherrer Institute, and Si Wu at the Chinese Academy of Sciences.
My research has been supported by Fudan University's Super Postdoctoral Program, the Shanghai Super Postdoctoral Program, and a General Program grant from the China Postdoctoral Science Foundation.
I study the thermodynamics, dynamics, and conformational behavior of biomacromolecules with complex free-energy landscapes, focusing on intrinsically disordered and disease-associated proteins. I also use insights into biomolecular behavior to rationally design new bionanomaterials with defined structures and functions.